Targeting the ATP-dependent formation of herpesvirus ribonucleoprotein particle assembly as an antiviral approach

Sophie Schumann,Brian R. Jackson,Ian Yule,Steven K. Whitehead,Charlotte Revill,Richard Foster,Adrian Whitehouse

Targeting the ATP-dependent formation of herpesvirus ribonucleoprotein particle assembly as an antiviral approach

2017

Sophie Schumann
Brian R. Jackson
Ian Yule
Steven K. Whitehead
Charlotte Revill
Richard Foster
Adrian Whitehouse

A small-molecule inhibitor that blocks the ATPase activity of the cellular human transcription/export complex (hTREX) protein UAP56 prevents the formation of Kaposi's sarcoma associated herpesvirus (KSHV) viral ribonucleoprotein particles (vRNPs)

Keywords:

Ribonucleoprotein particle
Transcription (biology)
Ribonucleoprotein
Virology
Molecular biology
ATPase
Biology
DNA polymerase
Viral resistance
atpase activity
Messenger RNA
Lytic cycle

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations