Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study
2019
Purpose
Limited available data suggest that older patients are more prone to develop paclitaxel-induced toxicity than their younger peers. It remains unclear whether this is related to age-dependent pharmacokinetics (PK) of paclitaxel. Primary objective of this study was to determine the influence of older age on the PK of paclitaxel.
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