The UCSC Xena Platform for cancer genomics data visualization and interpretation

UCSC Xena is a web-based visual integration and exploration tool for multi-omic data and associated clinical and phenotypic annotations. The investigator-driven platform consists of a web-based Xena Browser and turn-key Xena Hubs. Xena showcases seminal cancer genomics datasets from TCGA, Pan-Cancer Atlas, PCAWG, ICGC, GTEx, and the GDC; a total of more than 1500 datasets across 50 cancer types. We support virtually any type of functional genomics data modalities, including SNPs, INDELs, large structural variants, CNV, gene and other types of expression, DNA methylation, clinical and phenotypic annotations. A researcher can host their own data securely via private hubs running on a laptop or behind a firewall, with visual and analytical integration occurring only within the Xena Browser. Browser features include the high performance Visual Spreadsheet, dynamic Kaplan-Meier survival analysis, powerful filtering and subgrouping, charts, statistical analyses, genomic signatures, and bookmarks.