Study on the different decocting methods on Yinqiao San decoction of anti-inflammatory and antipyretic effects

Objective:To set up the most suitable decoction method by exploring different decocting methods on Yinqiao San decoction of anti-inflammatory and antipyretic pharmacological effects.Methods:Verification and comparison of the pharmacological effects of Yinqiao San with different decoction methods on the thermal model induced by dry yeast,thermal model induced by lipopolysacchride,acute inflammation model induced by egg white,capillary increased permeability model.Results:In the effect of medicine,the pharmacological effects of traditional decoction was much better than normal pressure decoction machine,and the pharmacological effects of normal pressure decoction machine was a little better than high pressure decoction machine which was consistent to the content determination of the five constituents and extraction.Conclusion:Traditional decoction methods,especially some special requirement should be respected.The traditional decoction method for Yinqiao San was better than others,and it was better to decoct two times in decoction machines.