Role of tubulin in the pathogenesis of fibrillary glomerulonephritis

: Fibrillary glomerulonephritis is a disease from a group of glomerular diseases with organized deposits. Its etiology and pathogenesis have not been studied. The paper deals with the clinical, morphological, immunohistochemical, and electron microscopic studies of 45 patients with fibrillary glomerulonephritis. The electron microscopic study revealed the microtubule pattern of fibrils in fibrillary glomerulonephritis. Comparative immunohistochemical analysis of the protein tubulin in nephrobiopsy specimens was made in patients with fibrillary glomerulonephritis and in those diagnosed as having minimal changes.