Clinical Study of Low Molecular Weight Heparin in Treatment of Fetal Growth Restriction

Objective To evaluate the clinical efficacy and safety of low molecular weight heparin in treatment of fetal growth restriction.Methods All 56 pregnant women with FGR were randomly divided into group A and group B,with 28 cases in each.Group A received low molecular weight heparin,and group B received low molecular weight dextran Salvia miltiorrhiza treatment.The pregnant women with preeclampsia were given antispasmodic and antihypertensive treatment.Results The height of the uterus,fetal biparietal diameter,femur length,head circumference,abdominal circumference,umbilical S/D values,changes in the amniotic fluid index,fetal biophysical score,birth weight,neonatal asphyxia of group A and group B were different(P0.05).Platelet count and coagulation parameters of before and after treatment were not significant different(P0.05).Conclusion The low molecular weight heparin helps to improve outcomes of patients with FGR.The low molecular weight heparin has good safety for the mother and fetus.