A kind of preparation method of ginkgo biloba p.e

The invention provides a kind of preparation method of ginkgo biloba p.e, this method is using ginkgo leaf as raw material, by alcohol or acetone, water are heavy, macroporous resin column purifies, boil water is heavy, macroporous resin column is secondarily purified, refrigeration precipitation, alcohol or acetone low-temperature water-soluble prepare ginkgo biloba p.e.Its product has the characteristics of water-soluble, low phenolic acid, low anthocyanidin, low residue on ignition, total flavonoids >=24%, terpene lactone >=9.5%, residue on ignition≤0.3%, OPC≤0.3%, total ginkgolic acid≤1ppm and cold water solubility >=5% wherein in ginkgo biloba p.e.This method realizes the quality for improving ginkgo biloba p.e using two step resin column methods and two-step precipitation, and technological operation is simple, goes phenolic acid effect good, process stabilizing, is adapted to industrialized production.