Bromodimethylsulfonium Bromide-Silver Triflate: A New Powerful Promoter System for the Activation of Thioglycosides

Bromodimethylsulfonium bromide (BDMS) in combination with silver triflate provides a very efficient thiophilic promoter system, capable of activating both "disarmed" and "armed" thioglycosides for glycosidic bond formation. The usefulness of this new promoter is illustrated by a successful reactivity-based one-pot oligosaccharide assembly.