Growth of Type 1 Neovascularization Following Cessation of Anti-Vascular Endothelial Growth Factor Therapy as a Possible Explanation for Treatment Resistance

Author Affiliations:Department of Ophthalmology, BC Children’s Hospital, Vancouver, British Columbia, Canada (Tsang, Dolman, Lyons); Department of Anatomical Pathology, BC Children’s Hospital, Vancouver, British Columbia, Canada (Senger); Division of Plastic Surgery, BC Children’s Hospital, Vancouver, British Columbia, Canada (Courtemanche); Division of Pediatric Hematology/Oncology/Blood andMarrow Transplantation, BC Children’s Hospital, Vancouver, British Columbia, Canada (Rassekh); Division of Pediatric Ophthalmology, Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada (Tsang, Lyons); Division of Oculoplastics/Orbit, Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, British Columbia, Canada (Dolman); Division of Plastic Surgery, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada (Courtemanche); Division of Hematology/Oncology/Blood andMarrow Transplant, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada (Rassekh); Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada (Senger).