Effects of Fluorides in the In Vitro Plaque Model System from Human Salivary Sediment

Artificial plaque from human saliva produces glycolytic action after three to four hours incubation at 37 C. When 6 to 8 ppm F from aminefluorides is present, such effects are absent. Under the same conditions, up to 100 ppm F from sodium fluoride and monofluorophosphate are inactive; stannous fluoride is active at 50 ppm F, but not at 10 ppm F. A marketed preparation of a gel that contains aminefluoride is active at 80 ppm F, whereas an inorganic fluoride gel is active only at 1,250 ppm F.