Cold Pain Threshold Identifies a Subgroup of Patients With Knee Osteoarthritis That Present With Multimodality Hyperalgesia and Elevated Pain Levels

Objectives:Cold hyperalgesia has been established as an important marker of pain severity in a number of conditions. This study aimed to establish the extent to which patients with knee osteoarthritis (OA) demonstrate widespread cold, heat, and pressure hyperalgesia. OA participants with widespread