EFFECT OF VARIOUS PLANT EXTRACTS ON HISTAMINE AEROSOL INDUCED BRONCHOSPASM IN GUINEA PIGS

The present study designed to evaluate the antiasthmatic activity of various plant extracts on histamine aerosol induced bronchospasm in guinea pigs. Histamine aerosol induced bronchospasm in guinea pigs showed that Thuja orientalis stem ethyl acetate extract inhibited bronchospasm of histamine (P<0.05) whereas Mangifera indica extract, Solanum melongena extract did not showed the bronchospasm of histamine. It is concluded that Thuja orientalis ethyl acetate extract possess antiasthmatic activity.