Quantification of Nanoparticle-mediated Alterations in Histological Tissue Sections Utilizing Quantitative Digital Holographic Phase Microscopy

Angelos Ntovas,Álvaro Barroso,Kai Eder,Antje Vennemann,Martin Wiemann,Jürgen Schnekenburger,Björn Kemper

Quantification of Nanoparticle-mediated Alterations in Histological Tissue Sections Utilizing Quantitative Digital Holographic Phase Microscopy

2021

Angelos Ntovas
Álvaro Barroso
Kai Eder
Antje Vennemann
Martin Wiemann
Jürgen Schnekenburger
Björn Kemper

We explored the capabilities of quantitative digital holographic phase microscopy to quantify nanomaterial-induced morphological alterations in unstained histological tissue sections by determination of refractive index changes.

Keywords:

Phase contrast microscopy
Refractive index
phase imaging
Nanoparticle
Biomedical engineering
Holography
tissue sections
Materials science

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