Accuracy of Clarius, handheld wireless point-of-care ultrasound (POCUS), in evaluating prostate morphology and volume compared to radical prostatectomy specimen weight: Is there a difference between transabdominal versus transrectal approach?
2021
Background: Prostate size estimation is a valuable clinical measure widely utilized in urology. This study evaluated the accuracy of preoperative transabdominal ultrasound (TAUS) compared to radical prostatectomy specimens and transrectal ultrasound (TRUS) in estimating prostate volume and identifying presence of median lobe, across different size groups, using the standard ellipsoid formula. The effect of median lobe on accuracy was also assessed. Materials and methods: Ninety-eight men undergoing robot-assisted radical prostatectomy were enrolled in this study. Preoperative evaluation of prostate volume was done using measurements obtained from TAUS using the Clarius C3 handheld wireless POCUS and from TRUS Clarius EC7. Participants were grouped based on prostate size ( 60g). Mean absolute percentage of error (MAPE) was used to evaluate accuracy. Mean percentage error determined if there was an overestimation or underestimation. Correlation between each TAUS size group, true prostate weight and TRUS was assessed. Results: Irrespective of BMI, TAUS accurately identified median lobe in all men. No statistically significant difference was found between specimen weight and TAUS prostate size for the >60g group. Amongst this same group, a strong correlation was noted between specimen weight and TAUS prostate size (r=0.911, p<0.001). There was also a strong correlation between TAUS and TRUS measurements for this group (r=0.950, p<0.001). Presence of median lobe did not have an impact on measurement accuracy. Conclusions: Bedside handheld wireless POCUS provides rapid, inexpensive, non-invasive and clinically accurate TAUS prostate assessments for larger prostates. Such features as identifying median lobes and measuring prostate volumes are valuable tools while patient counselling on lower urinary tract symptoms (LUTS), elevated prostate specific antigen (PSA) and benign prostate hyperplasia (BPH) surgical options.
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