Memantine Prevents Hypoglycemia-Induced Decrements of the Cerebral Energy Status in Healthy Subjects

Bastian Willenborg,André Schmoller,J. Caspary,Uwe H. Melchert,Harald G. Scholand-Engler,Kamila Jauch-Chara,Fritz Hohagen,Ulrich Schweiger,Kerstin M. Oltmanns

Memantine Prevents Hypoglycemia-Induced Decrements of the Cerebral Energy Status in Healthy Subjects

2011

Bastian Willenborg
André Schmoller
J. Caspary
Uwe H. Melchert
Harald G. Scholand-Engler
Kamila Jauch-Chara
Fritz Hohagen
Ulrich Schweiger
Kerstin M. Oltmanns

Memantine increases cerebral high energy phosphate levels upon hypoglycemia and may thereby represent a future option to protect the brain against cognitive decline in diabetes.

Keywords:

Hypoglycemia
Memantine
Internal medicine
Dementia
Endocrinology
Anesthesia
Phosphocreatine
Medicine
Diabetes mellitus
healthy subjects
cognitive decline
High-energy phosphate

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