Closed-loop Control of Fio2 Rapidly Identifies Need For Rescue Ventilation and Reduces Ards Severity in a Conscious Sheep Model of Burn and Smoke Inhalation Injury.

ABSTRACTPulmonary injury can be characterized by an increased need for fraction of inspired oxygen or inspired oxygen percentage (FiO2) to maintain arterial blood saturation of oxygenation (SaO2). We tested a smart oxygenation system (SOS) that uses the activity of a closed-loop control FiO2 algorit