023 CURRENT TRENDS IN INFECTIVE ENDOCARDITIS IN ITALY: REPORT ON 852 CASES FROM THE MULTICENTER, PROSPECTIVE SEI STUDY

and pulmonary and rheumatologic presentations were more frequent in Group I, whereas in Group II cardiac and abdominal presentations were more common. During hospitalization, septic shock (12.7% vs 18.9%; p = 0.021) was observed more frequently in Group II. There were no differences in periannular complications, heart failure, valvular dysfunction, persistent infection and embolism. In Group II the need of cardiac surgery was higher than in Group I (49.3 vs 58.7%; p 0.011). No differences were observed in hospital mortality (28.1% vs 28%). Conclusions: In the last years the incidence of infective endocarditis was higher in older patients with a higher degree of comorbidity. Prosthetic valve IE increased and IE in IVDU was less frequent. The need for cardiac surgery has also increased. Mortality remained similar.