TTS in Squirrel monkeys. I. Low‐frequency long duration noise

1976 
Little data has been gathered concerning TTS in primates following long‐term exposures to noise. In this study, squirrel monkeys were exposed to an octave band noise centered at 500 Hz for various durations up to 48 hours. Maximum TTS occurred at 750 and 500 Hz. An overall exposure SPL of 95 dB resulted in mean threshold shifts ranging from 7 dB for a 1‐h exposure to 20 dB for a 48‐h exposure. Recovery of TTS from all exposures at 95 dB SPL were complete within 48 hours for every subject. Comparison with the data of Melnick and Maves [Ann. Otol. 83, 820–828 (1974)] gathered on 10 human subjects indicates that both the development and recovery of TTS in squirrel monkeys is very similar to that found in humans for long‐term exposures. Presently, the development and recovery of TTS to an octave‐band noise centered at 4000 Hz is also being investigated. [This research supported by a Ford Foundation and an NIH grant to Henry Ford Hospital.]
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