Hemoglobin Aichi [α50(CE8) His → Arg]: a new slightly unstable hemoglobin variant discovered in Japan

Abstract A new abnormal hemoglobin, Hb Aichi [α50(CE8) His → Arg], was discovered in a young Japanese man. This variant was isoelectrofocussed between Hb A and Hb A 2 and amounted to about 21% of the total hemoglobin in the hemolysate. This hemoglobin showed normal oxygen affinity but slight instability.