Role of Epigenetics in Colorectal Cancer

In 2018 alone, colorectal cancer (CRC) accounted for 10.2% among all cancer cases. It is known to be a consequence of accumulated alterations in the genome. Several studies on genetics have improved our understanding of CRC. While genetics play its role as the first code of genome, role of epigenetics in CRC as the second code of genome has been highlighted in the last decades. We focus on the essential factors like DNA methylation drivers-writer, reader, eraser and non-coding RNA, miRNA and long non-coding RNAs associated with CRC.