Cation and ATP content of ferret red cells

Abstract Ferret red cells were shown to have the following properties: 1. 1. They have a high sodium (96 mmol/l cell) and low potassium (3.9 mmol/1 cell) content. 2. 2. The majority do not appear to have an active sodium pump in their membranes. 3. 3. Their membranes are highly permeable to rubidium indicating that they are probably also highly permeable to potassium. 4. 4. Their magnesium (3.01 mmol/1 cell) and calcium (0.01 mmol/1 cell) contents are similar to those of red cells from other species. 5. 5. Their ATP content (0.6 mmol/1 cell) is similar to that of cat and dog red cells and is sufficiently high to activate known ion transport systems.