Effects of frequency of treatment with recombinant equine somatotropin on selected biological responses in geldings

Abstract Two experiments compared the efficacies of different treatment frequencies for recombinant equine somatotropin (eST). In Experiment 1, five geldings received daily injections of eST at 20 μg/kg of body weight, and five received every-other-day injections at 40 μg/kg of body weight, for a total of 30 days. Plasma glucose ( P =0.0001), insulin ( P =0.0135), and non-esterified fatty acid (NEFA, P =0.0001) concentrations increased, and plasma urea nitrogen (PUN) concentrations decreased ( P =0.0001), in both groups, and only minor differences ( P P =0.0001) in both groups over time, and were higher ( P P P P