Analysis of drug sensitivity of Staphylococcus aureus in patients with chronic sinusitis

: Objective:To investigate the prevalence and drug sensitivity of nasal Staphylococcus aureus infection in patients with chronic sinusitis and healthy controls.Method:Bacterial culture and drug sensitivity test were performed in 71 patients with CRS (experimental group) and 103 healthy controls (control group). The infection rate of Staphylococcus aureus and the sensitivity of the drug were analyzed based on these results.Result:Twenty-nine Staphylococcus aureus strains were isolated from 71 cases of patients in the experimental group, and the positive rate was 40.85%; 12 Staphylococcus aureus strains were isolated from 103 cases of patients in the control group, and the positive rate was 11.65%. There was no significant difference between the experimental group and the control group in the sensitivity of the strains to aminoglycosides and glycopeptides.A total of 13 strains of methicillin resistant Staphylococcus aureus (MRSA) were detected, and there was no strains which had resistance to quinolones, aminoglycosides and vancomycin.Conclusion:The incidence of CRS may be related to the infection of Staphylococcus aureus. The use of antibiotics in the treatment of CRS should be based on the results of bacterial culture and drug sensitivity test.