L‐Tyrosine Hydrazide

[7662-51-3] C8H13N3O2 (MW 195.24) InChI = 1S/C9H13N3O2/c10-8(9(14)12-11)5-6-1-3-7(13)4-2-6/h1-4,8,13H,5,10-11H2,(H,12,14)/t8-/m0/s1 InChIKey = MWIXENPCUPDSOS-QMMMGPOBSA-N (resolution of carboxylic acids and amino acids1) Physical Data: crystalline solid; mp 196–198 °C; [α]25D +76° (c 4.2, 1N HCl). Solubility: slightly sol cold methanol or ethanol; readily sol hot methanol or ethanol. Form Supplied in: the free base (98% purity) is available from several commercial sources. No additional purification before use is required. Preparative Methods: the synthesis of l-tyrosine hydrazide from l-tyrosine has been described.2 d-Tyrosine hydrazide has been obtained by resolution of dl-tyrosine hydrazide with Cbz-l-proline.3 Handling, Storage, and Precautions: the free base is stable in amber bottles, at room temperature, for indefinite periods of time. No special handling precautions have been described.