Table 2. Apolipoprotein E (APOE) Genotype and Allele Frequencies in Patients With FTD and in the Subgroup With PPA Compared With Controls in Men (Upper Section) and in Women (Lower Section)

2016 
13 (19.4) 42 (25.3) .34 0.711 (0.353-1.430) 1 (5.6) .06 0.174 (0.022-1.345) e4/e4 1 (1.5) 1 (0.6) .50 2.500 (0.154-40.559) 0 (0) NA NA e2 10 (7.5) 20 (6.0) .57 1.258 (0.573-2.764) 5 (13.9) .08 2.516 (0.883-7.170) e3 104 (77.6) 266 (80.1) .54 0.860 (0.528-1.400) 26 (72.2) .27 0.645 (0.296-1.404) e4 20 (14.9) 46 (13.9) .76 1.091 (0.618-1.925) 5 (13.9) .99 1.003 (0.371-2.711) Abbreviations: CI, confidence interval; FTD, frontotemporal dementia; NA, not applicable; OR, odds ratio; PPA, primary progressive aphasia. a Significant values are in boldface. bAge-adjusted P=.04; OR, 5.655; 95% CI, 1.060-30.169. c Age-adjusted P=.001; OR, 21.687; 95% CI, 3.540-132.868.
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