Synthesis and characterisation of a doxorubicin-CNGRC peptide conjugate that targets tumour vasculature

Fabrice Anizon,F. Thomas Boyle,Julie Fisher,Philip Kocienski

Synthesis and characterisation of a doxorubicin-CNGRC peptide conjugate that targets tumour vasculature

2002

Fabrice Anizon
F. Thomas Boyle
Julie Fisher
Philip Kocienski

A conjugate between the cyclic peptide CNGRC and doxorubein, previously reported as a ligand of aminopeptidase N (CD13), has been synthesised and characterised.

Keywords:

Aminopeptidase N
Combinatorial chemistry
Doxorubicin
Angiogenesis
Cyclic peptide
Conjugate
Stereochemistry
Solid-phase synthesis
Chemistry
Peptide
Ligand
peptide conjugate

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