Clogging failure in microfilter for blood cell separation and its novel improvements

Clogging failure is common for microfilter utilizing the flat membrane structure. To reduce clogging failure in microfilters, the turbine blade-like micropillar is introduced in microfilter design. Two improved cross-flow microfilter designs employing the blade-like micropillar barrier are presented, one with varied cross-section channels, and the other with Archimedes' spiral channels. Analogy experimental-data based simulations show that the two aforementioned novel microfilters have good filtrating efficiency and fantastic anti-clogging characteristics. And the commercial value of the turbine blade-like barriers is affirmed by the industry Partners.