Synthesis of 5,7-Dioxo-6-halogenophenyl-6,7-dihydro-5H-dibenzo[a,c]cycloheptene Derivatives

The condensation of diphenic anhydride with o-, m- and p- halogenosubstituted phenylacetic acids gave the respective enolacetates Ia-Ie . The alkaline hydrolysis of these compounds yields the diketones IIa-IIe . After testing blood cloting agents in vivo, the last compounds showed indications of anticoagulants.