Этиология и патофизиология хронического интестинального псевдообструктивного синдрома у детей. I часть. Физиология моторики желудочно-кишечного тракта

Chronic intestinal pseudo-obstruction (CIPO) is a rare syndrome characterized by dilatation of the bowel lumen and abnormal motility in which no mechanical cause is identified. The syndrome appears at the background of congenital or acquired neuropathy, myopathy, or neuromyopathy. The article discusses the specifics of aetiopathogenesis of different disease forms, including de nova mutations discovered during the last decade. The article may be interested for surgeons who must be able to detect intestinal pseudo-obstruction to avoid unnecessary surgical interventions and also for other specialists who may encounter the syndrome in their practice.