Losses of chromosome arms 4q, 8p, 13q and gain of 8q are correlated with increasing chromosomal instability in hepatocellular carcinoma.

Sabine Hertz,Thomas Rothämel,Britta Skawran,Christian Giere,Doris Steinemann,Peer Flemming,T. Becker,Jacobus Flik,B. Wiese,Bisharah Soudah,Hans Kreipe,Brigitte Schlegelberger,Ludwig Wilkens

Losses of chromosome arms 4q, 8p, 13q and gain of 8q are correlated with increasing chromosomal instability in hepatocellular carcinoma.

2008

Sabine Hertz
Thomas Rothämel
Britta Skawran
Christian Giere
Doris Steinemann
Peer Flemming
T. Becker
Jacobus Flik
B. Wiese
Bisharah Soudah
Hans Kreipe
Brigitte Schlegelberger
Ludwig Wilkens

Objective: Chromosomal instability is a key feature in hepatocellular carcinoma (HCC). Array comparative genomic hybridization (aCGH) revealed recurring structural aberrations, wher

Keywords:

Comparative genomic hybridization
Virtual karyotype
Hepatocellular carcinoma
Chromosome instability
Fluorescence in situ hybridization
Biology
Genetics
Chromosome
Comparative Genome Hybridization
Molecular biology
fish analysis

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