Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment

Repeated administration of methamphetamine (METH) enhances acute locomotor responses to METH administered in the same context, a phenomenon termed as ‘locomotor sensitization’. Although many of the acute effects of METH are mediated by its influences on the compartmentalization of dopamine, serotoni