Diastereocontrolled Strecker reaction using (S)-5-phenylmorpholin-2-one
2001
Iminium ions derived from (S)-5-phenylmorpholin-2-one 1 undergo diastereoselective Strecker reactions using copper(I) cyanide and anhydrous hydrochloric acid; the major adducts may be degraded to D-α-amino acids.
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