The Influence of Korean Berchemia berchemiaefolia (Makino)Koidz Extract on Nonalcoholic Hepatic Steatosis in Rats

This study was designed to examine effects of Korean Berchemia berchemiaefolia (Makino) Koidz (BBK) on diet induced-fatty liver. 45 male SD rats were divided into three groups: normal diet (control group, n=15), 40% fat diet-induced obese rats (fat group, n=15), and BBK extract diet with 40% fat diet-induced obese rats (BBK group, n=15). Hematological and biochemical variables were measured. Total Received (April 20, 2015), Review Request(April 21, 2015), Review Result(May 06, 2015) Accepted(May 27, 2015), Published(June 30, 2015) (Corresponding Author) 609-757 Department of Clinical Laboratory Science, College of Health Sciences, Catholic University of Pusan, Busan ,Korea email: scchoi@cup.ac.kr 614-714 Department of Clinical Laboratory Science, College of Nursing & Healthcare Sciences, Dong-Eui University, Busan ,Korea email: 0167979575@nate.com 614-714 Department of Clinical Laboratory Science, College of Nursing & Healthcare Sciences, Dong-Eui University, Busan , Korea email: rokmagnum@naver.com *This paper was supported by RESEARCH FUND offered from Catholic University of Pusan This work was supported by the Brain Busan 21 Project in 2015. The Influence of Korean Berchemia berchemiaefolia (Makino) Koidz Extract on Nonalcoholic Hepatic Steatosis in Rats Copyright c 2015 HSST 132 leukocyte, neutrophil, neutrophil/lymphocyte ratio, erythrocyte, platelet, hemoglobin, and red distribution width levels were significantly lower than in BBK group than in fatty group. Glucose, total cholesterol, triglyceride, LDL-cholesterol, and BUN levels in BBK group were significantly lower than those of fatty group. BBK group showed significantly lower liver fatty degeneration (steatosis). These results suggest that Korean Berchemia berchemiaefolia (Makino) Koidz exerts anti-inflammatory, anti-obesity and ameliorative liver fatty degeneration effects.