Lactarius mushroom polysaccharide and its application
2012
The present invention discloses the structure and application Lactarius polysaccharides, Lactarius polysaccharide is a heteropolysaccharide composed of two monosaccharides, i.e., α-L- α-D- mannose, and xylose composition ratio 3:1 the average molecular weight of about 1.1 × 104D, having (1-6) α-L- mannose backbone, a → 3 connected to the 2-O) -α-D- xylose side chain, a dose of Lactarius polysaccharide can be significantly inhibited the growth of the transplanted S180 tumor. Intraperitoneal injection in 20mg / Kg.d, 40mg / Kg.d, 80mg / Kg.d groups (L1, L2, L3 groups) which inhibition rate of 44.358%, 52.326%, 68.422%, respectively, while the concentration of 20mg / Kg mannatide positive control group (M) inhibition rate was 57.727%, and the mice had no significant organ damage, toxic side effects, can significantly improve their immunity.
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