Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes

Kim et al. Page 1 of 35 Manuscript #200710028 Telomere dysfunction and cell survival: Roles for distinct TIN2-containing complexes Sahn-ho Kim 1,2 *, Albert R. Davalos 1 , Seok-Jin Heo 1 , Francis Rodier 1 , Ying Zou 1 , Christian Beausejour 1,3 , Patrick Kaminker 4,5 , Steven M. Yannone 1 & Judith Campisi 1,4 Lawrence Berkeley National Laboratory, Life Sciences Division, 1 Cyclotron Road, Berkeley, California 94720 USA Present address: Vattikuti Urology Institute, Henry Ford Health System, 1 Ford Place, 2D36, Detroit, MI 48202 USA Present address: Departement de Pharmacologie Centre de Recherche, CHU Ste-Justine, 3175 Cote Ste-Catherine, Montreal, Qc, H3T 1C5 Buck Institute for Age Research, 8001 Redwood Blvd., Novato, California 94945 USA Present address: Human Genome Sciences, 14200 Shady Grove Rd. Rockville, MD, 20850 USA *Correspondence: Sahn-Ho Kim, Vattikuti Urology Institute, Henry Ford Health System, 1 Ford Place, 2D36, Detroit, MI 48202 Telephone: 313-874-3249; Fax: 313-874-4324; Email: skim3@hfhs.org Keywords: Apoptosis/Senescence/DNA damage/Telomere complexes Running Title: Telomere complexes and cell survival. Numbers of character: 39,068