Quinazoline derivative used for cardio cerebrovascular diseases

The invention relates to a quinazoline derivative used for cardio cerebrovascular diseases, and particularly relates to a compound shown as a formula I, or a pharmaceutically acceptable salt, a solvate such as a hydrate, an ester and a prodrug of the compound, wherein substituents are as defined in the specification. The invention also relates to the use of the compound in preparation of drugs for preventing and/or treating cerebrovascular diseases of a mammal (such as people), as well as the use of the compound in preparation of drugs for preventing and/ or treating cardiovascular diseases or heart diseases of the mammal (such as people). The compound disclosed by the invention can be advantageously used for cerebral vascular diseases including but not limited to, cerebral thrombosis, cerebral ischemia, cerebral infarction and the like, as well as for cardiovascular diseases including but not limited to, myocardial infarction, myocardial ischemia, myocardial injury, coronary heart disease, angina, heart failure and the like.