MECHANISTIC INSIGHT INTO THE ROLE OF THE VON WILLEBRAND FACTOR-ANGIOPOIETIN-AXIS IN PULMONARY ARTERIOVENOUS MALFORMATIONS IN CHILDREN WITH A GLENN CIRCULATION

Infants that undergo a superior cavo-pulmonary connection (Glenn operation) frequently develop pulmonary arteriovenous malformations that cause cyanosis and clinical deterioration. The cause of abnormal pulmonary angiogenesis in these children is unknown but may be related to lack of hepatic