Genome-wide association study using whole-genome sequencing to identify a novel locus associated with cardiomyopathy risk in adult survivors of childhood cancer: Utility of a two-stage analytic approach.

Yadav Sapkota,Qi Liu,Kyla Shelton,Xuexia Wang,Carmen L. Wilson,Zhaoming Wang,Daniel A. Mulrooney,John L Jefferies,Kevin C. Oeffinger,Lindsay M. Morton,Jinghui Zhang,Gregory T. Armstrong,Smita Bhatia,Melissa M. Hudson,Leslie L. Robison,Yutaka Yasui

Genome-wide association study using whole-genome sequencing to identify a novel locus associated with cardiomyopathy risk in adult survivors of childhood cancer: Utility of a two-stage analytic approach.

2019

Yadav Sapkota
Qi Liu
Kyla Shelton
Xuexia Wang
Carmen L. Wilson
Zhaoming Wang
Daniel A. Mulrooney
John L Jefferies
Kevin C. Oeffinger
Lindsay M. Morton
Jinghui Zhang
Gregory T. Armstrong
Smita Bhatia
Melissa M. Hudson
Leslie L. Robison
Yutaka Yasui

1516Background: Survivors of childhood cancer are at increased risk of treatment-related cardiomyopathy, found to be modified by genetic factors. To further investigate genetic risks of cardiomyopa...

Keywords:

Cardiomyopathy
Locus (genetics)
Genome-wide association study
Computational biology
Cancer
Pathology
Whole genome sequencing
Medicine
increased risk
Bioinformatics
childhood cancer

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