Clinical and Experimental Study on Treatment of Acute RespiratoryTract Infection with Shuanghuanglian Aerosol(双黄连气雾剂 )

Two hundred and two cases of acute respiratory tract infection ( ARI) were treated withShuanghuanglian (SHL) aerosol. In these cases, the majority were virus infection and 64% of them wascaused by the respiratory syncytial virus (RSV) . The virostatic and bacteriostatic test were done in vitro bythe cell culture method and it was shown that SHL could inhibit the RSV, para-influenza virus I - IV and 23kinds of pathogenic bacteria such as Staphylococcus aureus etc. The bacteriostatic effect was positively cor-related to the SHL concentration. Experimental study showed that SHL could enhance the NK cell activity,promote the production of a-interferon and raise the rate of lymphocyte transformation. The controlled obser-vation on SHL preparation with various dosage-forms revealed that the SHL aerosol in treating early ARlshowed better results than that of injections and oral liquid symptomatologically ( P 0 . 05 ) . The total effec-tive rate was 96% .