Cascade hydroamination/redox reaction for the synthesis of cyclic aminals catalyzed by a combined gold complex and Brønsted acid.

Relay catalysis: An unprecedented protocol for the synthesis of cyclic aminals has been realized under the relay catalysis of a gold(I)/Bronsted acid binary system to generate cyclic aminals in excellent yields of up to 99 % with moderate to high diastereoselectivity (see scheme; up to 95:5 d.r.).