Superoxide dismutase activity in copper-deficient swine.

SummaryThese experiments demonstrate the dependency of cuprozinc superoxide dismutase activity in red cells and liver on an adequate dietary intake of copper. The superoxide dismutase activity in red cells decreased to 15% of control values and, therefore, these cells may be used as a convenient model for studying the physiologic consequences of free radicals.The authors are grateful for the technical assistance of Mr. George Trappett, Mr. Dale Chlarson, Ms. Jacqueline E. Thomas, and Mrs. Alice W. Tustison.