No association between the I105V polymorphism of the glutathione S-transferase P1 gene (GSTP1) and prostate cancer risk: a prospective study.

GSTs[3][1] conjugate glutathione to harmful substances facilitating their removal. Allelic variants of the GSTP1 gene have been identified, one isoleucine (GSTP1-1/I-105) and one valine (GSTP1-1/V-105) at codon 105. The allele frequency varies between ethnic groups. The isozymes have activities that