Syntheses based on 3,4-dimethyl-2-thioxothiazoline-5-carboxylic acid hydrazide and azide

Treatment of 3,4-dimethyl-2-thioxothiazoline-5-carboxylic acid hydrazide with NH4SCN and PhCONCS gave the corresponding thiosemicarbazides, arylsulfochlorides yielded the arylsulfonylhydrazides, and diazotization conditions gave the corresponding azide. The interactions of the latter with different nucleophiles have been studied and a series of novel carbamic acid, urea, and semicarbazide derivatives containing a thiazoline fragment have been prepared.