Etiopathogenetic methods of treating patients with chronic inflammatory-destructive periodontal diseases

This article presents the etiopathogenetic-based methods of treating patients with chronic generalized inflammatory-destructive periodontal diseases — periodontitis, which are mostly multicomponent and are performed in stages. The comprehensive therapy of inflammatory-destructive periodontal diseases should include the identification of common and local endogenous and exogenous parodontopathogenic factors and disease predictors, with the aim of normalizing the microbioprofile in periodontal pockets, providing osteoregeneratory, biostimulating, and normalizing effects on the microhemocirculation, relying on the achievements of genetics and epigenetics, personalized, and meet the requirements of evidence.