Surgery for cure followed by combined modality treatment for small cell bronchial carcinoma

For patients with small cell lung cancer (SCLC) at early stages surgery for cure is used to eliminate the primary tumour and its regional lymph-nodes followed by intermittent chemotherapy and radiotherapy within the first six postoperative months. After the pathohistological examination of the operation-specimen a two-arm-randomization is performed: standard chemotherapy compared with sequential chemotherapy using three different drug-combinations