Nodular Fasciitis and Myxolipoma of the Larynx: A rare case report with brief literature review

Nodular fasciitis (NF) is a peculiar, rapid-growing soft tissue lesion, typically appearing in subcutaneous tissue. 20% of NF occur in the head and neck region, where they can involve any anatomic site. Laryngeal involvement, however, is quite rare. On the contrary, Lipoma is recognized as a slow growing, benign mesenchymal tumour. Myxolipoma is a rare variant which has a prominent myxoid background. Laryngeal lipoma is infrequent, accounting for only 0.6% of all benign laryngeal lesions. Here, we report a unique case of adult laryngeal nodular fasciitis coexisting with myxolipoma in a 61-year-old male patient, describing their clinical and histopathological features, the strategies used to treat such conditions along with a brief review of the literature. The purpose is to broaden the differential diagnosis of rapid-growing laryngeal masses that cause airway obstruction and to stress the significance of integrative interdisciplinary collaboration on reaching an accurate diagnosis, thereby allowing proper management for benign pathologies and avoiding any futile aggressive treatment. Keywords: Nodular fasciitis, Larynx, Stridor, Myxolipoma.