An Alu-Mediated 6-kb Duplication in the BRCA1 Gene: A New Founder Mutation?

The authors would like to thank the family members. We also thank C. Bonnardel, T. Conway, J. Lynch, S. Slominski, and P. Watson for their expert assistance. This work was supported by program grants from le Comite Departemental de l'Ain et du Rhone de La Ligue contre le Cancer, la Fondation de France, la Fondation Adrienne et Pierre Sommer, Council for Tobacco Research grant 127DR@, U.S. Department of the Army grant DAMD17-94-J-4340, and the Nebraska State Cancer and Smoking-Related Diseases. N.P. is a fellow of the Ligue contre le Cancer de Haute-Savoie.