Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes

Laura Hedges,Susan Brown,A. Kenneth MacLeod,Audrey Vardy,Edward Doyle,Gina Song,Marjory Moreau,Miyoung Yoon,Thomas G. Osimitz,Brian G. Lake

Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes

2019

Laura Hedges
Susan Brown
A. Kenneth MacLeod
Audrey Vardy
Edward Doyle
Gina Song
Marjory Moreau
Miyoung Yoon
Thomas G. Osimitz
Brian G. Lake

AbstractThe metabolism of the pyrethroids deltamethrin (DLM), cis-permethrin (CPM) and trans-permethrin (TPM) was studied in human expressed cytochrome P450 (CYP) and carboxylesterase (CES) enzymes...

Keywords:

Deltamethrin
Cis–trans isomerism
Metabolism
Permethrin
Cytochrome P450
Enzyme
Carboxylesterase
Biochemistry
Chemistry
Liver cytosol

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