Bioluminescence Imaging in the Chick Chorioallantoic Membrane Assay.

For the analysis of tumorigenesis and therapeutic intervention, high throughput technologies that allow the detection of tumor size in the context of a living organism are of need. Here we describe the use of a chorioallantoic membrane model in the developing chick embryo on which growth of a tumor xenograft can be monitored over time, enabling bioluminescence technology.