Xenotropic and polytropic retrovirus receptor 1 (XPR1) promotes progression of tongue squamous cell carcinoma (TSCC) via activation of NF-κB signaling

Weichao Chen,Qiu Li Li,Qimei Pan,Huayong Zhang,Xiaoyan Fu,Fan Yao,Jianning Wang,An Kui Yang

Xenotropic and polytropic retrovirus receptor 1 (XPR1) promotes progression of tongue squamous cell carcinoma (TSCC) via activation of NF-κB signaling

2019

Weichao Chen
Qiu Li Li
Qimei Pan
Huayong Zhang
Xiaoyan Fu
Fan Yao
Jianning Wang
An Kui Yang

Background Xenotropic and polytropic retrovirus receptor 1 (XPR1), a previously identified cellular receptor for several murine leukemia viruses, plays a role in many pathophysiological processes. However, the role of XPR1 in human cancers has not yet been characterized.

Keywords:

Cancer research
Pathophysiology
Biology
Tongue squamous cell carcinoma
Retrovirus
Leukemia
NF-κB
Receptor
Immunohistochemistry
Ectopic expression
Gene silencing
Downregulation and upregulation
Molecular biology
Apoptosis
Blot

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